PDUFAoutcome: unknownconf 0.98

beremagene geperpavec — PDUFA

$KRYS · Krystal Biotech, Inc. · Dystrophic Epidermolysis Bullosa

Event date

May 19, 2023

1114 days ago

Sponsor runway

cash-flow +

$501.3M liquid

Evidence

“The Prescription Drug User Fee Act goal date has been extended by three months to May 19, 2023.”

Source: 8-K filed 2023-01-09View on EDGAR ↗0001711279-23-000003

Comparable historical pdufas· last 5 years · same indication

Ticker	Drug	Date	Outcome
$KRYS	beremagene geperpavec	2023-02-17	unknown

Recent insider activity· ±90 days

10 insiders · 0 buys · 49 sells

Grant

2023-06-30

Mazzacco Catherine

Director

2,180 @ ——

Grant

2023-06-30

Sutherland Everett Rand

Director

6,800 @ ——

Grant

2023-06-30

ROSSI DINO A

Director

6,800 @ ——

Grant

2023-06-30

Mason Christopher

Director

6,800 @ ——

Grant

2023-06-30

JANNEY DANIEL

Director

6,800 @ ——

Grant

2023-06-30

Gangolli Julian S

Director

6,800 @ ——

Sell10b5-1

2023-06-09

ORTH ANDREW C.

Chief Commercial Officer

5,261 @ $128.10$674K

Sell10b5-1

2023-06-09

ORTH ANDREW C.

Chief Commercial Officer

333 @ $129.70$43K

Sell10b5-1

2023-06-09

ORTH ANDREW C.

Chief Commercial Officer

6,906 @ $128.94$890K

Sell

2023-06-09

JANNEY DANIEL

Director

3,935 @ $129.29$509K

Sell

2023-06-09

JANNEY DANIEL

Director

5,000 @ $128.84$644K

Sell

2023-06-09

JANNEY DANIEL

Director

10,000 @ $128.53$1.29M

Exercise10b5-1

2023-06-09

ORTH ANDREW C.

Chief Commercial Officer

12,500 @ $63.55$794K

Sell

2023-06-08

JANNEY DANIEL

Director

5,388 @ $128.73$694K

Sell

2023-06-08

JANNEY DANIEL

Director

5,000 @ $127.96$640K

Sell

2023-06-08

JANNEY DANIEL

Director

10,000 @ $127.96$1.28M

Sell

2023-06-08

JANNEY DANIEL

Director

4,604 @ $127.96$589K

Sell

2023-06-08

JANNEY DANIEL

Director

1,073 @ $129.02$138K

Sell

2023-05-31

Krishnan Krish S

President and CEO

5,716 @ $116.95$668K

Sell

2023-05-31

Krishnan Krish S

President and CEO

400 @ $117.61$47K

Sell

2023-05-31

Krishnan Krish S

President and CEO

20,143 @ $115.98$2.34M

Sell

2023-05-31

Krishnan Krish S

President and CEO

4,557 @ $116.86$533K

Sell

2023-05-31

Krishnan Krish S

President and CEO

300 @ $117.57$35K

Sell

2023-05-31

Krishnan Suma

President, R&D

20,143 @ $115.98$2.34M

Sell

2023-05-31

Krishnan Suma

President, R&D

300 @ $117.57$35K

Sell

2023-05-31

Krishnan Suma

President, R&D

4,557 @ $116.86$533K

Sell

2023-05-31

Krishnan Suma

President, R&D

18,884 @ $116.00$2.19M

Sell

2023-05-31

Krishnan Suma

President, R&D

5,716 @ $116.95$668K

Sell

2023-05-31

Krishnan Suma

President, R&D

400 @ $117.61$47K

Sell

2023-05-31

Krishnan Krish S

President and CEO

18,884 @ $116.00$2.19M

Exercise10b5-1

2023-05-22

ROMANO KATHRYN

Chief Accounting Officer

1,300 @ $52.26$68K

Exercise10b5-1

2023-05-22

ROMANO KATHRYN

Chief Accounting Officer

2,521 @ $52.26$132K

Sell10b5-1

2023-05-22

ROMANO KATHRYN

Chief Accounting Officer

2,521 @ $105.80$267K

Exercise10b5-1

2023-05-22

ROMANO KATHRYN

Chief Accounting Officer

2,570 @ $52.26$134K

Sell10b5-1

2023-05-22

ROMANO KATHRYN

Chief Accounting Officer

2,570 @ $106.81$274K

Sell10b5-1

2023-05-22

ROMANO KATHRYN

Chief Accounting Officer

1,300 @ $107.88$140K

Exercise10b5-1

2023-05-22

ROMANO KATHRYN

Chief Accounting Officer

2,955 @ $52.26$154K

Sell10b5-1

2023-05-22

ROMANO KATHRYN

Chief Accounting Officer

2,955 @ $109.17$323K

Exercise10b5-1

2023-05-22

ROMANO KATHRYN

Chief Accounting Officer

3,154 @ $52.26$165K

Sell10b5-1

2023-05-22

ROMANO KATHRYN

Chief Accounting Officer

3,154 @ $109.99$347K

Exercise10b5-1

2023-05-22

ROMANO KATHRYN

Chief Accounting Officer

12,500 @ $63.55$794K

Sell10b5-1

2023-05-22

ROMANO KATHRYN

Chief Accounting Officer

12,500 @ $110.00$1.38M

Exercise10b5-1

2023-05-19

ROMANO KATHRYN

Chief Accounting Officer

12,500 @ $52.26$653K

Sell10b5-1

2023-05-19

ROMANO KATHRYN

Chief Accounting Officer

3,428 @ $95.08$326K

Sell10b5-1

2023-05-19

ROMANO KATHRYN

Chief Accounting Officer

12,500 @ $95.05$1.19M

Sell10b5-1

2023-05-19

JANNEY DANIEL

Director

50,000 @ $95.02$4.75M

Sell10b5-1

2023-05-09

JANNEY DANIEL

Director

17,100 @ $90.74$1.55M

Sell10b5-1

2023-04-19

JANNEY DANIEL

Director

7,900 @ $90.32$713K

Sell10b5-1

2023-04-17

Krishnan Suma

President, R&D

9,428 @ $87.41$824K

Sell10b5-1

2023-04-17

Krishnan Krish S

President and CEO

1,050 @ $85.55$90K

+ 25 more

Date	Insider	Action	Shares	Price	Value
2023-06-30	Mazzacco CatherineDirector	Grant	2,180	—	—
2023-06-30	Sutherland Everett RandDirector	Grant	6,800	—	—
2023-06-30	ROSSI DINO ADirector	Grant	6,800	—	—
2023-06-30	Mason ChristopherDirector	Grant	6,800	—	—
2023-06-30	JANNEY DANIELDirector	Grant	6,800	—	—
2023-06-30	Gangolli Julian SDirector	Grant	6,800	—	—
2023-06-09	ORTH ANDREW C.Chief Commercial Officer	Sell10b5-1	5,261	$128.10	$674K
2023-06-09	ORTH ANDREW C.Chief Commercial Officer	Sell10b5-1	333	$129.70	$43K
2023-06-09	ORTH ANDREW C.Chief Commercial Officer	Sell10b5-1	6,906	$128.94	$890K
2023-06-09	JANNEY DANIELDirector	Sell	3,935	$129.29	$509K
2023-06-09	JANNEY DANIELDirector	Sell	5,000	$128.84	$644K
2023-06-09	JANNEY DANIELDirector	Sell	10,000	$128.53	$1.29M
2023-06-09	ORTH ANDREW C.Chief Commercial Officer	Exercise10b5-1	12,500	$63.55	$794K
2023-06-08	JANNEY DANIELDirector	Sell	5,388	$128.73	$694K
2023-06-08	JANNEY DANIELDirector	Sell	5,000	$127.96	$640K
2023-06-08	JANNEY DANIELDirector	Sell	10,000	$127.96	$1.28M
2023-06-08	JANNEY DANIELDirector	Sell	4,604	$127.96	$589K
2023-06-08	JANNEY DANIELDirector	Sell	1,073	$129.02	$138K
2023-05-31	Krishnan Krish SPresident and CEO	Sell	5,716	$116.95	$668K
2023-05-31	Krishnan Krish SPresident and CEO	Sell	400	$117.61	$47K
2023-05-31	Krishnan Krish SPresident and CEO	Sell	20,143	$115.98	$2.34M
2023-05-31	Krishnan Krish SPresident and CEO	Sell	4,557	$116.86	$533K
2023-05-31	Krishnan Krish SPresident and CEO	Sell	300	$117.57	$35K
2023-05-31	Krishnan SumaPresident, R&D	Sell	20,143	$115.98	$2.34M
2023-05-31	Krishnan SumaPresident, R&D	Sell	300	$117.57	$35K
2023-05-31	Krishnan SumaPresident, R&D	Sell	4,557	$116.86	$533K
2023-05-31	Krishnan SumaPresident, R&D	Sell	18,884	$116.00	$2.19M
2023-05-31	Krishnan SumaPresident, R&D	Sell	5,716	$116.95	$668K
2023-05-31	Krishnan SumaPresident, R&D	Sell	400	$117.61	$47K
2023-05-31	Krishnan Krish SPresident and CEO	Sell	18,884	$116.00	$2.19M
2023-05-22	ROMANO KATHRYNChief Accounting Officer	Exercise10b5-1	1,300	$52.26	$68K
2023-05-22	ROMANO KATHRYNChief Accounting Officer	Exercise10b5-1	2,521	$52.26	$132K
2023-05-22	ROMANO KATHRYNChief Accounting Officer	Sell10b5-1	2,521	$105.80	$267K
2023-05-22	ROMANO KATHRYNChief Accounting Officer	Exercise10b5-1	2,570	$52.26	$134K
2023-05-22	ROMANO KATHRYNChief Accounting Officer	Sell10b5-1	2,570	$106.81	$274K
2023-05-22	ROMANO KATHRYNChief Accounting Officer	Sell10b5-1	1,300	$107.88	$140K
2023-05-22	ROMANO KATHRYNChief Accounting Officer	Exercise10b5-1	2,955	$52.26	$154K
2023-05-22	ROMANO KATHRYNChief Accounting Officer	Sell10b5-1	2,955	$109.17	$323K
2023-05-22	ROMANO KATHRYNChief Accounting Officer	Exercise10b5-1	3,154	$52.26	$165K
2023-05-22	ROMANO KATHRYNChief Accounting Officer	Sell10b5-1	3,154	$109.99	$347K
2023-05-22	ROMANO KATHRYNChief Accounting Officer	Exercise10b5-1	12,500	$63.55	$794K
2023-05-22	ROMANO KATHRYNChief Accounting Officer	Sell10b5-1	12,500	$110.00	$1.38M
2023-05-19	ROMANO KATHRYNChief Accounting Officer	Exercise10b5-1	12,500	$52.26	$653K
2023-05-19	ROMANO KATHRYNChief Accounting Officer	Sell10b5-1	3,428	$95.08	$326K
2023-05-19	ROMANO KATHRYNChief Accounting Officer	Sell10b5-1	12,500	$95.05	$1.19M
2023-05-19	JANNEY DANIELDirector	Sell10b5-1	50,000	$95.02	$4.75M
2023-05-09	JANNEY DANIELDirector	Sell10b5-1	17,100	$90.74	$1.55M
2023-04-19	JANNEY DANIELDirector	Sell10b5-1	7,900	$90.32	$713K
2023-04-17	Krishnan SumaPresident, R&D	Sell10b5-1	9,428	$87.41	$824K
2023-04-17	Krishnan Krish SPresident and CEO	Sell10b5-1	1,050	$85.55	$90K

+ 25 more transactions

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