NDA/BLA filedconf 0.95

exagamglogene autotemcel — NDA/BLA filed

$CRSP · CRISPR Therapeutics AG · severe sickle cell disease (SCD)

Event date

Date TBD

Sponsor runway

6+ yrs

$2.44B liquid

Evidence

“FDA Accepts Biologics License Applications for exagamglogene autotemcel (exa-cel) for Severe Sickle Cell Disease and Transfusion-Dependent Beta Thalassemia”

Source: Press release · 2023-06-09View press release ↗

Comparable historical nda/bla fileds· last 5 years · same indication

Ticker	Drug	Date	Outcome
$CRSP	exagamglogene autotemcel	2023-06-08	unknown

Recent insider activity· ±90 days

4 insiders · 0 buys · 10 sells

Sell

2026-03-23

Kulkarni Samarth

Chief Executive Officer

10,020 @ $46.78$469K

Sell

2026-03-23

Prasad Raju

Chief Financial Officer

3,708 @ $46.78$173K

Sell

2026-03-23

KASINGER JAMES R.

General Counsel and Secretary

3,182 @ $46.78$149K

Grant

2026-03-20

Prasad Raju

Chief Financial Officer

27,500 @ ——

Exercise

2026-03-20

KASINGER JAMES R.

General Counsel and Secretary

6,250 @ ——

Exercise

2026-03-20

Prasad Raju

Chief Financial Officer

6,250 @ ——

Grant

2026-03-20

Prasad Raju

Chief Financial Officer

38,499 @ ——

Grant

2026-03-20

Patel Naimish

Chief Medical Officer

38,499 @ ——

Grant

2026-03-20

Patel Naimish

Chief Medical Officer

30,000 @ ——

Grant

2026-03-20

KASINGER JAMES R.

General Counsel and Secretary

38,499 @ ——

Grant

2026-03-20

KASINGER JAMES R.

General Counsel and Secretary

25,000 @ ——

Exercise

2026-03-20

Kulkarni Samarth

Chief Executive Officer

19,687 @ ——

Grant

2026-03-20

Kulkarni Samarth

Chief Executive Officer

114,249 @ ——

Grant

2026-03-20

Kulkarni Samarth

Chief Executive Officer

81,875 @ ——

Gift

2026-03-16

Prasad Raju

Chief Financial Officer

750 @ ——

Sell

2026-03-16

Kulkarni Samarth

Chief Executive Officer

10,349 @ $48.26$499K

Sell

2026-03-16

KASINGER JAMES R.

General Counsel and Secretary

3,450 @ $48.26$166K

Sell

2026-03-16

Prasad Raju

Chief Financial Officer

5,848 @ $48.26$282K

Sell

2026-03-16

Patel Naimish

Chief Medical Officer

3,150 @ $48.26$152K

Sell

2026-03-16

Prasad Raju

Chief Financial Officer

4,021 @ $48.26$194K

Exercise

2026-03-14

Prasad Raju

Chief Financial Officer

6,875 @ ——

Exercise

2026-03-14

Patel Naimish

Chief Medical Officer

8,125 @ ——

Exercise

2026-03-14

Kulkarni Samarth

Chief Executive Officer

20,625 @ ——

Exercise

2026-03-14

Prasad Raju

Chief Financial Officer

10,000 @ ——

Exercise

2026-03-14

KASINGER JAMES R.

General Counsel and Secretary

6,875 @ ——

Sell

2026-03-11

KASINGER JAMES R.

General Counsel and Secretary

2,800 @ $52.80$148K

Sell

2026-03-11

Kulkarni Samarth

Chief Executive Officer

9,798 @ $52.80$517K

Exercise

2026-03-10

Kulkarni Samarth

Chief Executive Officer

19,250 @ ——

Exercise

2026-03-10

KASINGER JAMES R.

General Counsel and Secretary

5,500 @ ——

Date	Insider	Action	Shares	Price	Value
2026-03-23	Kulkarni SamarthChief Executive Officer	Sell	10,020	$46.78	$469K
2026-03-23	Prasad RajuChief Financial Officer	Sell	3,708	$46.78	$173K
2026-03-23	KASINGER JAMES R.General Counsel and Secretary	Sell	3,182	$46.78	$149K
2026-03-20	Prasad RajuChief Financial Officer	Grant	27,500	—	—
2026-03-20	KASINGER JAMES R.General Counsel and Secretary	Exercise	6,250	—	—
2026-03-20	Prasad RajuChief Financial Officer	Exercise	6,250	—	—
2026-03-20	Prasad RajuChief Financial Officer	Grant	38,499	—	—
2026-03-20	Patel NaimishChief Medical Officer	Grant	38,499	—	—
2026-03-20	Patel NaimishChief Medical Officer	Grant	30,000	—	—
2026-03-20	KASINGER JAMES R.General Counsel and Secretary	Grant	38,499	—	—
2026-03-20	KASINGER JAMES R.General Counsel and Secretary	Grant	25,000	—	—
2026-03-20	Kulkarni SamarthChief Executive Officer	Exercise	19,687	—	—
2026-03-20	Kulkarni SamarthChief Executive Officer	Grant	114,249	—	—
2026-03-20	Kulkarni SamarthChief Executive Officer	Grant	81,875	—	—
2026-03-16	Prasad RajuChief Financial Officer	Gift	750	—	—
2026-03-16	Kulkarni SamarthChief Executive Officer	Sell	10,349	$48.26	$499K
2026-03-16	KASINGER JAMES R.General Counsel and Secretary	Sell	3,450	$48.26	$166K
2026-03-16	Prasad RajuChief Financial Officer	Sell	5,848	$48.26	$282K
2026-03-16	Patel NaimishChief Medical Officer	Sell	3,150	$48.26	$152K
2026-03-16	Prasad RajuChief Financial Officer	Sell	4,021	$48.26	$194K
2026-03-14	Prasad RajuChief Financial Officer	Exercise	6,875	—	—
2026-03-14	Patel NaimishChief Medical Officer	Exercise	8,125	—	—
2026-03-14	Kulkarni SamarthChief Executive Officer	Exercise	20,625	—	—
2026-03-14	Prasad RajuChief Financial Officer	Exercise	10,000	—	—
2026-03-14	KASINGER JAMES R.General Counsel and Secretary	Exercise	6,875	—	—
2026-03-11	KASINGER JAMES R.General Counsel and Secretary	Sell	2,800	$52.80	$148K
2026-03-11	Kulkarni SamarthChief Executive Officer	Sell	9,798	$52.80	$517K
2026-03-10	Kulkarni SamarthChief Executive Officer	Exercise	19,250	—	—
2026-03-10	KASINGER JAMES R.General Counsel and Secretary	Exercise	5,500	—	—

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