Yeji
CRLconf 0.99

zynyz — CRL

$INCY · INCYTE CORP
Event date
February 27, 2026
99 days ago
Sponsor runway
cash-flow +
$3.46B liquid

Evidence

“On February 27, 2026, the U.S. Food and Drug Administration ("FDA") issued a Complete Response Letter ("CRL") for the supplemental Biologics License Application ("sBLA") for Zynyz® (retifanlimab-dlwr) injection (375mg) for an additional indication for the treatment of adult patients with metastatic non-small cell lung cancer ("NSCLC") in combination with platinum-based chemotherapy.”
Source: 8-K filed 2026-03-06View on EDGAR ↗0000879169-26-000013

Comparable historical crls· last 5 years · same event type

No comparable historical outcomes in our database yet — backfill of past readouts arrives next ingestion cycle.

Recent insider activity· ±90 days

15 insiders · 0 buys · 15 sells
Exercise10b5-1
2026-05-19
Clancy Paul J
Director
15,000 @ $84.53$1.27M
Sell10b5-1
2026-05-19
Clancy Paul J
Director
15,000 @ $94.93$1.42M
Exercise
2026-05-08
BAKER BROS. ADVISORS LP
Director
15,000 @ $84.53$1.27M
Grant
2026-05-04
Upadhyay Suketu
EVP & Chief Financial Officer
13,171 @ ——
Grant
2026-05-04
Upadhyay Suketu
EVP & Chief Financial Officer
38,429 @ ——
Grant
2026-05-04
Upadhyay Suketu
EVP & Chief Financial Officer
26,343 @ ——
Exercise10b5-1
2026-04-17
CAGNONI PABLO J
President, Global Head of R&D
12,590 @ $71.93$906K
Sell10b5-1
2026-04-17
CAGNONI PABLO J
President, Global Head of R&D
18,667 @ $96.50$1.80M
Exercise10b5-1
2026-04-17
CAGNONI PABLO J
President, Global Head of R&D
6,077 @ $64.25$390K
Grant
2026-04-15
CAGNONI PABLO J
President, Global Head of R&D
27,892 @ ——
Exercise
2026-04-15
Meury William
Chief Executive Officer
125,000 @ ——
Grant
2026-04-15
Stein Steven H
CMO & Head of Late-Stage Dev.
39,049 @ ——
Grant
2026-03-31
BAKER BROS. ADVISORS LP
Director
421 @ ——
Grant
2026-03-31
HARRIGAN EDMUND
Director
269 @ $94.12$25K
Grant
2026-03-31
Clancy Paul J
Director
265 @ $94.12$25K
Tax
2026-03-25
Trotta Matteo
EVP, GM, Dermatology US
537 @ $92.23$50K
Exercise10b5-1
2026-03-17
CAGNONI PABLO J
President, Global Head of R&D
11,501 @ $64.25$739K
Exercise10b5-1
2026-03-17
CAGNONI PABLO J
President, Global Head of R&D
7,166 @ $61.18$438K
Sell10b5-1
2026-03-17
CAGNONI PABLO J
President, Global Head of R&D
18,667 @ $94.24$1.76M
Exercise10b5-1
2026-02-19
CAGNONI PABLO J
President, Global Head of R&D
13,093 @ $61.76$809K
Exercise10b5-1
2026-02-19
CAGNONI PABLO J
President, Global Head of R&D
5,575 @ $61.18$341K
Sell10b5-1
2026-02-19
CAGNONI PABLO J
President, Global Head of R&D
18,668 @ $100.91$1.88M
Tax
2026-02-02
Morrissey Michael James
EVP, Head of Tech. Operations
185 @ $102.67$19K
Tax
2026-02-02
Heeson Lee
EVP, Head of Incyte Intl
111 @ $102.67$11K
Tax
2026-01-20
Morrissey Michael James
EVP, Head of Tech. Operations
429 @ $102.62$44K
Grant
2026-01-16
Tray Thomas
Principal Accounting Officer
2,425 @ ——
Grant
2026-01-16
Heeson Lee
EVP, Head of Incyte Intl
8,911 @ ——
Grant
2026-01-16
CAGNONI PABLO J
President, Global Head of R&D
28,475 @ ——
Grant
2026-01-16
Stein Steven H
CMO & Head of Late-Stage Dev.
19,932 @ ——
Grant
2026-01-16
Issa Mohamed Khairie
EVP, Head of US Oncology
14,237 @ ——
Grant
2026-01-16
Trotta Matteo
EVP, GM, Dermatology US
8,542 @ ——
Grant
2026-01-16
Mayes Patrick A
EVP & Chief Scientific Officer
4,218 @ ——
Grant
2026-01-16
Morrissey Michael James
EVP, Head of Tech. Operations
7,426 @ ——
Sell10b5-1
2026-01-07
Issa Mohamed Khairie
EVP, Head of US Oncology
10,856 @ $109.07$1.18M
Tax10b5-1
2026-01-06
Issa Mohamed Khairie
EVP, Head of US Oncology
8,264 @ $106.66$881K
Sell10b5-1
2026-01-05
Stein Steven H
CMO & Head of Late-Stage Dev.
15,634 @ $101.70$1.59M
Grant
2025-12-31
Clancy Paul J
Director
241 @ $98.77$24K
Grant
2025-12-31
HARRIGAN EDMUND
Director
245 @ $98.77$24K
Tax
2025-12-31
Stein Steven H
CMO & Head of Late-Stage Dev.
13,292 @ $98.77$1.31M
Tax
2025-12-31
Morrissey Michael James
EVP, Head of Tech. Operations
254 @ $98.77$25K
Grant
2025-12-31
BAKER BROS. ADVISORS LP
Director
328 @ ——
Exercise10b5-1
2025-12-19
Tray Thomas
Principal Accounting Officer
1,044 @ $95.76$100K
Exercise10b5-1
2025-12-19
Tray Thomas
Principal Accounting Officer
1,730 @ $95.76$166K
Sell10b5-1
2025-12-19
Tray Thomas
Principal Accounting Officer
2,774 @ $100.00$277K
Sell10b5-1
2025-12-18
Tray Thomas
Principal Accounting Officer
600 @ $98.25$59K
Sell10b5-1
2025-12-17
Morrissey Michael James
EVP, Head of Tech. Operations
4,323 @ $97.26$420K
Sell10b5-1
2025-12-16
Morrissey Michael James
EVP, Head of Tech. Operations
833 @ $97.42$81K
Sell10b5-1
2025-12-16
Morrissey Michael James
EVP, Head of Tech. Operations
53,175 @ $97.29$5.17M
Sell10b5-1
2025-12-11
Mayes Patrick A
EVP & Chief Scientific Officer
255 @ $94.94$24K
Sell10b5-1
2025-12-10
Mayes Patrick A
EVP & Chief Scientific Officer
5,553 @ $95.58$531K
+ 8 more
← All catalysts for $INCY