AdComconf 0.98

omecamtiv mecarbil — AdCom

$CYTK · CYTOKINETICS INC · heart failure with reduced ejection fraction (HFrEF)

Event date

December 13, 2022

1271 days ago

Sponsor runway

3 mo

$129.8M liquid

Evidence

“Cytokinetics, Incorporated today announced that the U.S. Food & Drug Administration (FDA) Cardiovascular and Renal Drugs Advisory Committee (CRDAC) voted 8 to 3 that the benefits of omecamtiv mecarbil do not outweigh its risks for the treatment of heart failure with reduced ejection fraction (HFrEF).”

Source: 8-K filed 2022-12-14View on EDGAR ↗0000950170-22-026478

Comparable historical adcoms· last 5 years · same event type

No comparable historical outcomes in our database yet — backfill of past readouts arrives next ingestion cycle.

Recent insider activity· ±90 days

12 insiders · 0 buys · 23 sells

Sell

2023-03-09

Malik Fady Ibraham

EVP Research & Development

4,000 @ $39.10$156K

Tax

2023-03-06

Blum Robert I

President & CEO

11,900 @ $39.13$466K

Grant

2023-03-06

Wong Robert

VP, Chief Accounting Officer

6,000 @ ——

Grant

2023-03-06

Wong Robert

VP, Chief Accounting Officer

2,464 @ ——

Grant

2023-03-06

Wong Robert

VP, Chief Accounting Officer

9,536 @ ——

Grant

2023-03-06

Malik Fady Ibraham

EVP Research & Development

40,000 @ ——

Grant

2023-03-06

Malik Fady Ibraham

EVP Research & Development

2,555 @ ——

Grant

2023-03-06

Malik Fady Ibraham

EVP Research & Development

77,445 @ ——

Grant

2023-03-06

Jaw Ching

SVP Finance & CFO

30,000 @ ——

Grant

2023-03-06

Jaw Ching

SVP Finance & CFO

2,555 @ ——

Grant

2023-03-06

Jaw Ching

SVP Finance & CFO

47,445 @ ——

Grant

2023-03-06

Callos Andrew

EVP, Chief Commercial Officer

30,000 @ ——

Grant

2023-03-06

Callos Andrew

EVP, Chief Commercial Officer

2,555 @ ——

Grant

2023-03-06

Callos Andrew

EVP, Chief Commercial Officer

47,445 @ ——

Grant

2023-03-06

Blum Robert I

President & CEO

82,500 @ ——

Grant

2023-03-06

Blum Robert I

President & CEO

2,555 @ ——

Grant

2023-03-06

Blum Robert I

President & CEO

162,445 @ ——

Tax

2023-03-06

Wong Robert

VP, Chief Accounting Officer

692 @ $39.13$27K

Tax

2023-03-06

Malik Fady Ibraham

EVP Research & Development

4,958 @ $39.13$194K

Tax

2023-03-06

Jaw Ching

SVP Finance & CFO

2,403 @ $39.13$94K

Sell

2023-03-06

Blum Robert I

President & CEO

12,500 @ $39.94$499K

Exercise

2023-03-06

Blum Robert I

President & CEO

12,500 @ $9.65$121K

Tax

2023-03-02

Callos Andrew

EVP, Chief Commercial Officer

2,202 @ $39.60$87K

Tax

2023-03-02

Blum Robert I

President & CEO

32,724 @ $39.60$1.30M

Tax

2023-03-02

Wong Robert

VP, Chief Accounting Officer

2,484 @ $39.60$98K

Tax

2023-03-02

Malik Fady Ibraham

EVP Research & Development

10,785 @ $39.60$427K

Tax

2023-03-02

Jaw Ching

SVP Finance & CFO

6,225 @ $39.60$247K

Sell

2023-02-21

Wong Robert

VP, Chief Accounting Officer

2,234 @ $45.21$101K

Tax

2023-02-16

Callos Andrew

EVP, Chief Commercial Officer

969 @ $44.13$43K

Tax

2023-02-16

Blum Robert I

President & CEO

3,230 @ $44.13$143K

Tax

2023-02-16

Wong Robert

VP, Chief Accounting Officer

510 @ $44.13$23K

Tax

2023-02-16

Malik Fady Ibraham

EVP Research & Development

1,513 @ $44.13$67K

Tax

2023-02-16

Jaw Ching

SVP Finance & CFO

1,210 @ $44.13$53K

Gift

2023-02-10

Malik Fady Ibraham

EVP Research & Development

150 @ ——

Sell

2023-02-09

Malik Fady Ibraham

EVP Research & Development

4,000 @ $43.73$175K

Sell

2023-02-09

Malik Fady Ibraham

EVP Research & Development

7,000 @ $43.74$306K

Exercise

2023-02-09

Malik Fady Ibraham

EVP Research & Development

7,000 @ $7.96$56K

Sell

2023-02-06

WIERENGA WENDALL

Director

7,000 @ $45.00$315K

Exercise

2023-02-06

WIERENGA WENDALL

Director

7,000 @ $6.72$47K

Exercise

2023-02-03

Jaw Ching

SVP Finance & CFO

15,000 @ $12.10$182K

Sell

2023-02-03

Jaw Ching

SVP Finance & CFO

15,000 @ $45.00$675K

Sell

2023-02-03

Wong Robert

VP, Chief Accounting Officer

3,004 @ $45.00$135K

Exercise

2023-01-17

Blum Robert I

President & CEO

10,000 @ $9.65$97K

Sell

2023-01-17

Blum Robert I

President & CEO

10,000 @ $42.43$424K

Sell

2023-01-12

Malik Fady Ibraham

EVP Research & Development

4,000 @ $40.47$162K

Sell

2023-01-04

Blum Robert I

President & CEO

10,000 @ $44.24$442K

Exercise

2023-01-04

Blum Robert I

President & CEO

10,000 @ $9.65$97K

Grant

2023-01-03

SMITH SANDFORD D

Director

253 @ $44.35$11K

Grant

2023-01-03

HENDERSON JOHN T

Director

450 @ $44.35$20K

Grant

2023-01-03

Harrington Robert Arthur

Director

253 @ $44.35$11K

+ 30 more

Date	Insider	Action	Shares	Price	Value
2023-03-09	Malik Fady IbrahamEVP Research & Development	Sell	4,000	$39.10	$156K
2023-03-06	Blum Robert IPresident & CEO	Tax	11,900	$39.13	$466K
2023-03-06	Wong RobertVP, Chief Accounting Officer	Grant	6,000	—	—
2023-03-06	Wong RobertVP, Chief Accounting Officer	Grant	2,464	—	—
2023-03-06	Wong RobertVP, Chief Accounting Officer	Grant	9,536	—	—
2023-03-06	Malik Fady IbrahamEVP Research & Development	Grant	40,000	—	—
2023-03-06	Malik Fady IbrahamEVP Research & Development	Grant	2,555	—	—
2023-03-06	Malik Fady IbrahamEVP Research & Development	Grant	77,445	—	—
2023-03-06	Jaw ChingSVP Finance & CFO	Grant	30,000	—	—
2023-03-06	Jaw ChingSVP Finance & CFO	Grant	2,555	—	—
2023-03-06	Jaw ChingSVP Finance & CFO	Grant	47,445	—	—
2023-03-06	Callos AndrewEVP, Chief Commercial Officer	Grant	30,000	—	—
2023-03-06	Callos AndrewEVP, Chief Commercial Officer	Grant	2,555	—	—
2023-03-06	Callos AndrewEVP, Chief Commercial Officer	Grant	47,445	—	—
2023-03-06	Blum Robert IPresident & CEO	Grant	82,500	—	—
2023-03-06	Blum Robert IPresident & CEO	Grant	2,555	—	—
2023-03-06	Blum Robert IPresident & CEO	Grant	162,445	—	—
2023-03-06	Wong RobertVP, Chief Accounting Officer	Tax	692	$39.13	$27K
2023-03-06	Malik Fady IbrahamEVP Research & Development	Tax	4,958	$39.13	$194K
2023-03-06	Jaw ChingSVP Finance & CFO	Tax	2,403	$39.13	$94K
2023-03-06	Blum Robert IPresident & CEO	Sell	12,500	$39.94	$499K
2023-03-06	Blum Robert IPresident & CEO	Exercise	12,500	$9.65	$121K
2023-03-02	Callos AndrewEVP, Chief Commercial Officer	Tax	2,202	$39.60	$87K
2023-03-02	Blum Robert IPresident & CEO	Tax	32,724	$39.60	$1.30M
2023-03-02	Wong RobertVP, Chief Accounting Officer	Tax	2,484	$39.60	$98K
2023-03-02	Malik Fady IbrahamEVP Research & Development	Tax	10,785	$39.60	$427K
2023-03-02	Jaw ChingSVP Finance & CFO	Tax	6,225	$39.60	$247K
2023-02-21	Wong RobertVP, Chief Accounting Officer	Sell	2,234	$45.21	$101K
2023-02-16	Callos AndrewEVP, Chief Commercial Officer	Tax	969	$44.13	$43K
2023-02-16	Blum Robert IPresident & CEO	Tax	3,230	$44.13	$143K
2023-02-16	Wong RobertVP, Chief Accounting Officer	Tax	510	$44.13	$23K
2023-02-16	Malik Fady IbrahamEVP Research & Development	Tax	1,513	$44.13	$67K
2023-02-16	Jaw ChingSVP Finance & CFO	Tax	1,210	$44.13	$53K
2023-02-10	Malik Fady IbrahamEVP Research & Development	Gift	150	—	—
2023-02-09	Malik Fady IbrahamEVP Research & Development	Sell	4,000	$43.73	$175K
2023-02-09	Malik Fady IbrahamEVP Research & Development	Sell	7,000	$43.74	$306K
2023-02-09	Malik Fady IbrahamEVP Research & Development	Exercise	7,000	$7.96	$56K
2023-02-06	WIERENGA WENDALLDirector	Sell	7,000	$45.00	$315K
2023-02-06	WIERENGA WENDALLDirector	Exercise	7,000	$6.72	$47K
2023-02-03	Jaw ChingSVP Finance & CFO	Exercise	15,000	$12.10	$182K
2023-02-03	Jaw ChingSVP Finance & CFO	Sell	15,000	$45.00	$675K
2023-02-03	Wong RobertVP, Chief Accounting Officer	Sell	3,004	$45.00	$135K
2023-01-17	Blum Robert IPresident & CEO	Exercise	10,000	$9.65	$97K
2023-01-17	Blum Robert IPresident & CEO	Sell	10,000	$42.43	$424K
2023-01-12	Malik Fady IbrahamEVP Research & Development	Sell	4,000	$40.47	$162K
2023-01-04	Blum Robert IPresident & CEO	Sell	10,000	$44.24	$442K
2023-01-04	Blum Robert IPresident & CEO	Exercise	10,000	$9.65	$97K
2023-01-03	SMITH SANDFORD DDirector	Grant	253	$44.35	$11K
2023-01-03	HENDERSON JOHN TDirector	Grant	450	$44.35	$20K
2023-01-03	Harrington Robert ArthurDirector	Grant	253	$44.35	$11K

+ 30 more transactions

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