FDA approvalconf 0.99

wainua — FDA approval

$IONS · IONIS PHARMACEUTICALS INC · polyneuropathy of hereditary transthyretin-mediated amyloidosis in adults

Event date

December 21, 2023

898 days ago

Sponsor runway

7 mo

$1.92B liquid

Evidence

“the U.S. Food and Drug Administration has approved Ionis' and AstraZeneca's WAINUA™ (eplontersen) for the treatment of the polyneuropathy of hereditary transthyretin-mediated amyloidosis in adults”

Source: 8-K filed 2023-12-22View on EDGAR ↗0001140361-23-058974

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$ETON	desmoda	2026-02-25	success

Recent insider activity· ±90 days

14 insiders · 0 buys · 49 sells

Other

2024-02-29

Geary Richard S

EVP, Chief Development Officer

604 @ $34.42$21K

Other

2024-02-29

Monia Brett P

Chief Executive Officer

538 @ $34.42$19K

Other

2024-02-29

Swayze Eric

EVP Research

605 @ $34.42$21K

Other

2024-02-29

Birchler Brian

EVP, Corp and Development Ops

604 @ $34.42$21K

Other

2024-02-29

BENNETT C FRANK

EVP, Chief Scientific Officer

383 @ $34.42$13K

Grant

2024-02-26

Jenne Kyle

EVP, Chf GL Pdt Str Ofcr

65,203 @ ——

Sell10b5-1

2024-02-16

Monia Brett P

Chief Executive Officer

387 @ $44.49$17K

Sell

2024-02-02

Monia Brett P

Chief Executive Officer

23,501 @ $49.37$1.16M

Sell

2024-02-02

Geary Richard S

EVP, Chief Development Officer

1,961 @ $50.04$98K

Sell

2024-02-02

Schneider Eugene

EVP, Chf Clinical Develop Ofcr

2,071 @ $49.59$103K

Sell10b5-1

2024-02-02

Swayze Eric

EVP Research

1,907 @ $49.56$95K

Sell

2024-02-02

Cadoret-Manier Onaiza

EVP, Chf GL Pdt Str & Oper Ofc

2,125 @ $49.60$105K

Sell

2024-02-02

HOUGEN ELIZABETH L

EVP, Finance & CFO

2,125 @ $49.54$105K

Sell

2024-02-02

O'NEIL PATRICK R.

EVP CLO & General Counsel

1,961 @ $49.67$97K

Sell

2024-02-02

BENNETT C FRANK

EVP, Chief Scientific Officer

1,853 @ $49.52$92K

Grant

2024-02-01

Monia Brett P

Chief Executive Officer

25,372 @ ——

Grant

2024-02-01

Geary Richard S

EVP, Chief Development Officer

3,820 @ ——

Grant

2024-02-01

BENNETT C FRANK

EVP, Chief Scientific Officer

3,609 @ ——

Grant

2024-02-01

O'NEIL PATRICK R.

EVP CLO & General Counsel

3,820 @ ——

Grant

2024-02-01

Monia Brett P

Chief Executive Officer

20,416 @ ——

Grant10b5-1

2024-02-01

Swayze Eric

EVP Research

3,715 @ ——

Grant

2024-02-01

Cadoret-Manier Onaiza

EVP, Chf GL Pdt Str & Oper Ofc

4,140 @ ——

Grant

2024-02-01

HOUGEN ELIZABETH L

EVP, Finance & CFO

4,140 @ ——

Grant

2024-02-01

Schneider Eugene

EVP, Chf Clinical Develop Ofcr

4,033 @ ——

Sell10b5-1

2024-01-31

Swayze Eric

EVP Research

10,773 @ $52.00$560K

Sell10b5-1

2024-01-25

O'NEIL PATRICK R.

EVP CLO & General Counsel

6,450 @ $51.75$334K

Sell10b5-1

2024-01-25

Monia Brett P

Chief Executive Officer

2,285 @ $51.75$118K

Sell

2024-01-17

Monia Brett P

Chief Executive Officer

32,059 @ $50.42$1.62M

Sell

2024-01-17

Baroldi Joseph

EVP, Chief Business Officer

564 @ $50.42$28K

Sell

2024-01-17

BENNETT C FRANK

EVP, Chief Scientific Officer

6,745 @ $50.42$340K

Sell

2024-01-17

Birchler Brian

EVP, Corp and Development Ops

4,497 @ $50.42$227K

Sell

2024-01-17

Swayze Eric

EVP Research

6,296 @ $50.42$317K

Sell

2024-01-17

Swayze Eric

EVP Research

9 @ $50.42$454

Sell

2024-01-17

Cadoret-Manier Onaiza

EVP, Chf GL Pdt Str & Oper Ofc

5,564 @ $50.42$281K

Sell

2024-01-17

O'NEIL PATRICK R.

EVP CLO & General Counsel

7,744 @ $50.42$390K

Sell

2024-01-17

Schneider Eugene

EVP, Chf Clinical Develop Ofcr

5,482 @ $50.42$276K

Sell

2024-01-17

HOUGEN ELIZABETH L

EVP, Finance & CFO

8,683 @ $50.42$438K

Sell

2024-01-17

Baroldi Joseph

EVP, Chief Business Officer

1,460 @ $50.42$74K

Sell

2024-01-17

Geary Richard S

EVP, Chief Development Officer

7,338 @ $50.42$370K

Exercise

2024-01-16

Monia Brett P

Chief Executive Officer

68,084 @ ——

Exercise

2024-01-16

Birchler Brian

EVP, Corp and Development Ops

12,080 @ ——

Exercise

2024-01-16

Geary Richard S

EVP, Chief Development Officer

19,852 @ ——

Exercise

2024-01-16

Cadoret-Manier Onaiza

EVP, Chf GL Pdt Str & Oper Ofc

15,062 @ ——

Exercise

2024-01-16

O'NEIL PATRICK R.

EVP CLO & General Counsel

20,641 @ ——

Exercise

2024-01-16

Baroldi Joseph

EVP, Chief Business Officer

1,353 @ ——

Exercise

2024-01-16

Baroldi Joseph

EVP, Chief Business Officer

3,688 @ ——

Exercise

2024-01-16

Schneider Eugene

EVP, Chf Clinical Develop Ofcr

15,162 @ ——

Exercise

2024-01-16

Swayze Eric

EVP Research

17,069 @ ——

Exercise

2024-01-16

Swayze Eric

EVP Research

21 @ ——

Exercise

2024-01-16

HOUGEN ELIZABETH L

EVP, Finance & CFO

22,487 @ ——

+ 88 more

Date	Insider	Action	Shares	Price	Value
2024-02-29	Geary Richard SEVP, Chief Development Officer	Other	604	$34.42	$21K
2024-02-29	Monia Brett PChief Executive Officer	Other	538	$34.42	$19K
2024-02-29	Swayze EricEVP Research	Other	605	$34.42	$21K
2024-02-29	Birchler BrianEVP, Corp and Development Ops	Other	604	$34.42	$21K
2024-02-29	BENNETT C FRANKEVP, Chief Scientific Officer	Other	383	$34.42	$13K
2024-02-26	Jenne KyleEVP, Chf GL Pdt Str Ofcr	Grant	65,203	—	—
2024-02-16	Monia Brett PChief Executive Officer	Sell10b5-1	387	$44.49	$17K
2024-02-02	Monia Brett PChief Executive Officer	Sell	23,501	$49.37	$1.16M
2024-02-02	Geary Richard SEVP, Chief Development Officer	Sell	1,961	$50.04	$98K
2024-02-02	Schneider EugeneEVP, Chf Clinical Develop Ofcr	Sell	2,071	$49.59	$103K
2024-02-02	Swayze EricEVP Research	Sell10b5-1	1,907	$49.56	$95K
2024-02-02	Cadoret-Manier OnaizaEVP, Chf GL Pdt Str & Oper Ofc	Sell	2,125	$49.60	$105K
2024-02-02	HOUGEN ELIZABETH LEVP, Finance & CFO	Sell	2,125	$49.54	$105K
2024-02-02	O'NEIL PATRICK R.EVP CLO & General Counsel	Sell	1,961	$49.67	$97K
2024-02-02	BENNETT C FRANKEVP, Chief Scientific Officer	Sell	1,853	$49.52	$92K
2024-02-01	Monia Brett PChief Executive Officer	Grant	25,372	—	—
2024-02-01	Geary Richard SEVP, Chief Development Officer	Grant	3,820	—	—
2024-02-01	BENNETT C FRANKEVP, Chief Scientific Officer	Grant	3,609	—	—
2024-02-01	O'NEIL PATRICK R.EVP CLO & General Counsel	Grant	3,820	—	—
2024-02-01	Monia Brett PChief Executive Officer	Grant	20,416	—	—
2024-02-01	Swayze EricEVP Research	Grant10b5-1	3,715	—	—
2024-02-01	Cadoret-Manier OnaizaEVP, Chf GL Pdt Str & Oper Ofc	Grant	4,140	—	—
2024-02-01	HOUGEN ELIZABETH LEVP, Finance & CFO	Grant	4,140	—	—
2024-02-01	Schneider EugeneEVP, Chf Clinical Develop Ofcr	Grant	4,033	—	—
2024-01-31	Swayze EricEVP Research	Sell10b5-1	10,773	$52.00	$560K
2024-01-25	O'NEIL PATRICK R.EVP CLO & General Counsel	Sell10b5-1	6,450	$51.75	$334K
2024-01-25	Monia Brett PChief Executive Officer	Sell10b5-1	2,285	$51.75	$118K
2024-01-17	Monia Brett PChief Executive Officer	Sell	32,059	$50.42	$1.62M
2024-01-17	Baroldi JosephEVP, Chief Business Officer	Sell	564	$50.42	$28K
2024-01-17	BENNETT C FRANKEVP, Chief Scientific Officer	Sell	6,745	$50.42	$340K
2024-01-17	Birchler BrianEVP, Corp and Development Ops	Sell	4,497	$50.42	$227K
2024-01-17	Swayze EricEVP Research	Sell	6,296	$50.42	$317K
2024-01-17	Swayze EricEVP Research	Sell	9	$50.42	$454
2024-01-17	Cadoret-Manier OnaizaEVP, Chf GL Pdt Str & Oper Ofc	Sell	5,564	$50.42	$281K
2024-01-17	O'NEIL PATRICK R.EVP CLO & General Counsel	Sell	7,744	$50.42	$390K
2024-01-17	Schneider EugeneEVP, Chf Clinical Develop Ofcr	Sell	5,482	$50.42	$276K
2024-01-17	HOUGEN ELIZABETH LEVP, Finance & CFO	Sell	8,683	$50.42	$438K
2024-01-17	Baroldi JosephEVP, Chief Business Officer	Sell	1,460	$50.42	$74K
2024-01-17	Geary Richard SEVP, Chief Development Officer	Sell	7,338	$50.42	$370K
2024-01-16	Monia Brett PChief Executive Officer	Exercise	68,084	—	—
2024-01-16	Birchler BrianEVP, Corp and Development Ops	Exercise	12,080	—	—
2024-01-16	Geary Richard SEVP, Chief Development Officer	Exercise	19,852	—	—
2024-01-16	Cadoret-Manier OnaizaEVP, Chf GL Pdt Str & Oper Ofc	Exercise	15,062	—	—
2024-01-16	O'NEIL PATRICK R.EVP CLO & General Counsel	Exercise	20,641	—	—
2024-01-16	Baroldi JosephEVP, Chief Business Officer	Exercise	1,353	—	—
2024-01-16	Baroldi JosephEVP, Chief Business Officer	Exercise	3,688	—	—
2024-01-16	Schneider EugeneEVP, Chf Clinical Develop Ofcr	Exercise	15,162	—	—
2024-01-16	Swayze EricEVP Research	Exercise	17,069	—	—
2024-01-16	Swayze EricEVP Research	Exercise	21	—	—
2024-01-16	HOUGEN ELIZABETH LEVP, Finance & CFO	Exercise	22,487	—	—

+ 88 more transactions

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