FDA approvaloutcome: successconf 1.00

vyxeos — FDA approval

$JAZZ · Jazz Pharmaceuticals plc

Event date

January 27, 2026

130 days ago

Sponsor runway

cash-flow +

$1.84B liquid

Evidence

“openFDA SUPPL (EFFICACY) approval of VYXEOS — application NDA209401”

Source ↗

Comparable historical fda approvals· last 5 years · same event type

100% hit rate (10/10)

Ticker	Drug	Date	Outcome
$INCY	zynyz	2026-05-18	success
$INCY	jakafi xr	2026-05-01	success
$AXSM	auvelity	2026-04-30	success
$INCY	zynyz	2026-03-30	success
$BIIB	spinraza	2026-03-27	success
$CORT	lifyorli	2026-03-25	success
$RYTM	imcivree	2026-03-19	success
$ASND	yuviwel	2026-02-27	success
$BMRN	palynziq	2026-02-27	success
$ETON	desmoda	2026-02-25	success

Recent insider activity· ±90 days

13 insiders · 0 buys · 38 sells

Sell10b5-1

2026-04-01

COZADD BRUCE C

Director

3,684 @ $190.22$701K

Sell10b5-1

2026-04-01

COZADD BRUCE C

Director

24 @ $191.74$5K

Sell10b5-1

2026-04-01

COZADD BRUCE C

Director

2,292 @ $190.94$438K

Sell

2026-03-09

Carr Patricia

SVP, Chief Accounting Officer

1,287 @ $182.94$235K

Tax

2026-03-05

Johnson Philip L

EVP & Chief Financial Officer

2,615 @ $188.69$493K

Tax

2026-03-05

Patil Neena M

EVP & Chief Legal Officer

5,000 @ $188.69$943K

Tax

2026-03-05

COZADD BRUCE C

Director

15,114 @ $188.69$2.85M

Tax

2026-03-05

Henderson Mary Elizabeth

SVP, Technical Operations

1,394 @ $186.75$260K

Tax

2026-03-05

Pearce Samantha

EVP, Chief Commercial Officer

2,503 @ $188.69$472K

Tax

2026-03-05

Iannone Robert

EVP, Global Head of R&D & CMO

6,209 @ $188.69$1.17M

Tax

2026-03-05

Carr Patricia

SVP, Chief Accounting Officer

1,436 @ $186.77$268K

Tax

2026-03-05

GALA RENEE D

President & CEO

7,065 @ $188.69$1.33M

Sell10b5-1

2026-03-03

COZADD BRUCE C

Director

3,159 @ $186.09$588K

Sell10b5-1

2026-03-03

COZADD BRUCE C

Director

233 @ $187.84$44K

Sell10b5-1

2026-03-03

COZADD BRUCE C

Director

2,608 @ $186.73$487K

Sell

2026-02-27

Carr Patricia

SVP, Chief Accounting Officer

1,117 @ $190.91$213K

Exercise

2026-02-27

RIEDEL NORBERT G

Director

3,415 @ $138.08$472K

Sell

2026-02-27

RIEDEL NORBERT G

Director

3,415 @ $192.00$656K

Sell

2026-02-26

Patil Neena M

EVP & Chief Legal Officer

875 @ $192.07$168K

Exercise

2026-02-26

Patil Neena M

EVP & Chief Legal Officer

27,084 @ $137.12$3.71M

Sell

2026-02-26

Patil Neena M

EVP & Chief Legal Officer

15,555 @ $190.28$2.96M

Exercise

2026-02-26

Patil Neena M

EVP & Chief Legal Officer

2,916 @ $137.12$400K

Sell

2026-02-26

Patil Neena M

EVP & Chief Legal Officer

2,916 @ $189.81$553K

Grant

2026-02-26

Patil Neena M

EVP & Chief Legal Officer

10,079 @ ——

Sell

2026-02-26

Patil Neena M

EVP & Chief Legal Officer

3,523 @ $193.58$682K

Sell

2026-02-26

Patil Neena M

EVP & Chief Legal Officer

11,529 @ $191.65$2.21M

Sell

2026-02-26

Patil Neena M

EVP & Chief Legal Officer

1,061 @ $190.00$202K

Sell

2026-02-26

Patil Neena M

EVP & Chief Legal Officer

549 @ $190.80$105K

Sell

2026-02-26

Patil Neena M

EVP & Chief Legal Officer

1,784 @ $191.88$342K

Sell

2026-02-26

Henderson Mary Elizabeth

SVP, Technical Operations

5,343 @ $194.49$1.04M

Grant

2026-02-26

GALA RENEE D

President & CEO

44,465 @ ——

Grant

2026-02-26

Johnson Philip L

EVP & Chief Financial Officer

11,857 @ ——

Grant

2026-02-26

LOVE TED W

Director

1,527 @ ——

Grant

2026-02-26

Carr Patricia

SVP, Chief Accounting Officer

2,223 @ ——

Sell

2026-02-26

Carr Patricia

SVP, Chief Accounting Officer

1,253 @ $194.11$243K

Grant

2026-02-26

Henderson Mary Elizabeth

SVP, Technical Operations

4,447 @ ——

Grant

2026-02-26

Pearce Samantha

EVP, Chief Commercial Officer

9,782 @ ——

Grant

2026-02-26

Iannone Robert

EVP, Global Head of R&D & CMO

14,822 @ ——

Sell

2026-02-26

Patil Neena M

EVP & Chief Legal Officer

197 @ $193.60$38K

Sell

2026-02-26

Patil Neena M

EVP & Chief Legal Officer

1,009 @ $192.79$195K

Exercise

2026-02-26

Patil Neena M

EVP & Chief Legal Officer

20,125 @ $113.10$2.28M

Sell

2026-02-26

Patil Neena M

EVP & Chief Legal Officer

16,602 @ $192.53$3.20M

Exercise

2026-02-26

Patil Neena M

EVP & Chief Legal Officer

875 @ $113.10$99K

Grant

2026-01-16

GALA RENEE D

President & CEO

12,741 @ ——

Grant

2026-01-16

Henderson Mary Elizabeth

SVP, Technical Operations

10,116 @ ——

Tax

2026-01-16

GALA RENEE D

President & CEO

5,371 @ $171.16$919K

Grant

2026-01-16

Carr Patricia

SVP, Chief Accounting Officer

2,370 @ ——

Grant

2026-01-16

Patil Neena M

EVP & Chief Legal Officer

8,852 @ ——

Disp

2026-01-16

Patil Neena M

EVP & Chief Legal Officer

3,275 @ $171.16$561K

Grant

2026-01-16

Iannone Robert

EVP, Global Head of R&D & CMO

11,699 @ ——

+ 30 more

Date	Insider	Action	Shares	Price	Value
2026-04-01	COZADD BRUCE CDirector	Sell10b5-1	3,684	$190.22	$701K
2026-04-01	COZADD BRUCE CDirector	Sell10b5-1	24	$191.74	$5K
2026-04-01	COZADD BRUCE CDirector	Sell10b5-1	2,292	$190.94	$438K
2026-03-09	Carr PatriciaSVP, Chief Accounting Officer	Sell	1,287	$182.94	$235K
2026-03-05	Johnson Philip LEVP & Chief Financial Officer	Tax	2,615	$188.69	$493K
2026-03-05	Patil Neena MEVP & Chief Legal Officer	Tax	5,000	$188.69	$943K
2026-03-05	COZADD BRUCE CDirector	Tax	15,114	$188.69	$2.85M
2026-03-05	Henderson Mary ElizabethSVP, Technical Operations	Tax	1,394	$186.75	$260K
2026-03-05	Pearce SamanthaEVP, Chief Commercial Officer	Tax	2,503	$188.69	$472K
2026-03-05	Iannone RobertEVP, Global Head of R&D & CMO	Tax	6,209	$188.69	$1.17M
2026-03-05	Carr PatriciaSVP, Chief Accounting Officer	Tax	1,436	$186.77	$268K
2026-03-05	GALA RENEE DPresident & CEO	Tax	7,065	$188.69	$1.33M
2026-03-03	COZADD BRUCE CDirector	Sell10b5-1	3,159	$186.09	$588K
2026-03-03	COZADD BRUCE CDirector	Sell10b5-1	233	$187.84	$44K
2026-03-03	COZADD BRUCE CDirector	Sell10b5-1	2,608	$186.73	$487K
2026-02-27	Carr PatriciaSVP, Chief Accounting Officer	Sell	1,117	$190.91	$213K
2026-02-27	RIEDEL NORBERT GDirector	Exercise	3,415	$138.08	$472K
2026-02-27	RIEDEL NORBERT GDirector	Sell	3,415	$192.00	$656K
2026-02-26	Patil Neena MEVP & Chief Legal Officer	Sell	875	$192.07	$168K
2026-02-26	Patil Neena MEVP & Chief Legal Officer	Exercise	27,084	$137.12	$3.71M
2026-02-26	Patil Neena MEVP & Chief Legal Officer	Sell	15,555	$190.28	$2.96M
2026-02-26	Patil Neena MEVP & Chief Legal Officer	Exercise	2,916	$137.12	$400K
2026-02-26	Patil Neena MEVP & Chief Legal Officer	Sell	2,916	$189.81	$553K
2026-02-26	Patil Neena MEVP & Chief Legal Officer	Grant	10,079	—	—
2026-02-26	Patil Neena MEVP & Chief Legal Officer	Sell	3,523	$193.58	$682K
2026-02-26	Patil Neena MEVP & Chief Legal Officer	Sell	11,529	$191.65	$2.21M
2026-02-26	Patil Neena MEVP & Chief Legal Officer	Sell	1,061	$190.00	$202K
2026-02-26	Patil Neena MEVP & Chief Legal Officer	Sell	549	$190.80	$105K
2026-02-26	Patil Neena MEVP & Chief Legal Officer	Sell	1,784	$191.88	$342K
2026-02-26	Henderson Mary ElizabethSVP, Technical Operations	Sell	5,343	$194.49	$1.04M
2026-02-26	GALA RENEE DPresident & CEO	Grant	44,465	—	—
2026-02-26	Johnson Philip LEVP & Chief Financial Officer	Grant	11,857	—	—
2026-02-26	LOVE TED WDirector	Grant	1,527	—	—
2026-02-26	Carr PatriciaSVP, Chief Accounting Officer	Grant	2,223	—	—
2026-02-26	Carr PatriciaSVP, Chief Accounting Officer	Sell	1,253	$194.11	$243K
2026-02-26	Henderson Mary ElizabethSVP, Technical Operations	Grant	4,447	—	—
2026-02-26	Pearce SamanthaEVP, Chief Commercial Officer	Grant	9,782	—	—
2026-02-26	Iannone RobertEVP, Global Head of R&D & CMO	Grant	14,822	—	—
2026-02-26	Patil Neena MEVP & Chief Legal Officer	Sell	197	$193.60	$38K
2026-02-26	Patil Neena MEVP & Chief Legal Officer	Sell	1,009	$192.79	$195K
2026-02-26	Patil Neena MEVP & Chief Legal Officer	Exercise	20,125	$113.10	$2.28M
2026-02-26	Patil Neena MEVP & Chief Legal Officer	Sell	16,602	$192.53	$3.20M
2026-02-26	Patil Neena MEVP & Chief Legal Officer	Exercise	875	$113.10	$99K
2026-01-16	GALA RENEE DPresident & CEO	Grant	12,741	—	—
2026-01-16	Henderson Mary ElizabethSVP, Technical Operations	Grant	10,116	—	—
2026-01-16	GALA RENEE DPresident & CEO	Tax	5,371	$171.16	$919K
2026-01-16	Carr PatriciaSVP, Chief Accounting Officer	Grant	2,370	—	—
2026-01-16	Patil Neena MEVP & Chief Legal Officer	Grant	8,852	—	—
2026-01-16	Patil Neena MEVP & Chief Legal Officer	Disp	3,275	$171.16	$561K
2026-01-16	Iannone RobertEVP, Global Head of R&D & CMO	Grant	11,699	—	—

+ 30 more transactions

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