FDA approvaloutcome: successconf 1.00

brineura — FDA approval

$BMRN · BIOMARIN PHARMACEUTICAL INC

Event date

July 24, 2024

682 days ago

Sponsor runway

cash-flow +

$2.22B liquid

Evidence

“openFDA SUPPL (EFFICACY) approval of BRINEURA — application BLA761052”

Source ↗

Comparable historical fda approvals· last 5 years · same event type

100% hit rate (10/10)

Ticker	Drug	Date	Outcome
$INCY	zynyz	2026-05-18	success
$INCY	jakafi xr	2026-05-01	success
$AXSM	auvelity	2026-04-30	success
$INCY	zynyz	2026-03-30	success
$BIIB	spinraza	2026-03-27	success
$CORT	lifyorli	2026-03-25	success
$RYTM	imcivree	2026-03-19	success
$ASND	yuviwel	2026-02-27	success
$BMRN	palynziq	2026-02-27	success
$ETON	desmoda	2026-02-25	success

Recent insider activity· ±90 days

19 insiders · 0 buys · 8 sells

Grant

2024-09-30

Friberg Gregory R

EVP, Chief R&D Officer

49,850 @ ——

Grant

2024-09-30

Friberg Gregory R

EVP, Chief R&D Officer

7,870 @ ——

Grant

2024-09-30

Friberg Gregory R

EVP, Chief R&D Officer

21,190 @ ——

Tax

2024-09-13

FUCHS HENRY J

President, Worldwide R&D

12,098 @ $84.90$1.03M

Sell10b5-1

2024-08-13

Burkhart Erin

GVP, Chief Accounting Officer

714 @ $90.00$64K

Tax

2024-06-28

Mueller Brian

EVP, Chief Financial Officer

588 @ $82.33$48K

Tax

2024-06-03

HERON ELAINE J

Director

4,168 @ $76.41$318K

Exercise

2024-06-03

HERON ELAINE J

Director

5,047 @ $63.10$318K

Tax

2024-06-03

MEIER RICHARD A

Director

5,451 @ $76.41$417K

Exercise

2024-06-03

MEIER RICHARD A

Director

6,600 @ $63.10$416K

Exercise10b5-1

2024-05-30

Mueller Brian

EVP, Chief Financial Officer

5,000 @ $63.10$316K

Sell10b5-1

2024-05-30

Mueller Brian

EVP, Chief Financial Officer

5,000 @ $75.19$376K

Exercise10b5-1

2024-05-28

Davis George Eric

EVP, Chief Legal Officer

40,850 @ $63.10$2.58M

Sell10b5-1

2024-05-28

Davis George Eric

EVP, Chief Legal Officer

38,071 @ $74.45$2.83M

Sell10b5-1

2024-05-28

Davis George Eric

EVP, Chief Legal Officer

2,779 @ $75.29$209K

Grant

2024-05-21

Dere Willard H

Director

4,720 @ ——

Grant

2024-05-21

HERON ELAINE J

Director

4,720 @ ——

Grant

2024-05-21

MEIER RICHARD A

Director

7,080 @ ——

Grant

2024-05-21

Bodem Barbara W.

Director

4,720 @ ——

Grant

2024-05-21

ANDERSON ELIZABETH M

Director

4,720 @ ——

Grant

2024-05-21

PYOTT DAVID E I

Director

4,720 @ ——

Grant

2024-05-21

Countouriotis Athena

Director

4,720 @ ——

Grant

2024-05-21

Enyedy Mark J

Director

4,720 @ ——

Grant

2024-05-21

HOMBACH ROBERT J.

Director

4,720 @ ——

Grant

2024-05-21

Ho Maykin

Director

4,720 @ ——

Grant

2024-05-20

Hubbard Cristin

EVP, Chief Commercial Officer

4,700 @ ——

Grant

2024-05-20

Hubbard Cristin

EVP, Chief Commercial Officer

14,690 @ ——

Grant

2024-05-20

Hubbard Cristin

EVP, Chief Commercial Officer

33,520 @ ——

Tax

2024-05-20

BIENAIME JEAN JACQUES

Director

1,202 @ $77.05$93K

Tax

2024-05-17

Burkhart Erin

GVP, Chief Accounting Officer

993 @ $76.97$76K

Exercise10b5-1

2024-05-10

BIENAIME JEAN JACQUES

Director

20,000 @ $63.10$1.26M

Sell10b5-1

2024-05-10

BIENAIME JEAN JACQUES

Director

20,000 @ $81.14$1.62M

Exercise10b5-1

2024-05-09

BIENAIME JEAN JACQUES

Director

20,000 @ $63.10$1.26M

Sell10b5-1

2024-05-09

BIENAIME JEAN JACQUES

Director

20,000 @ $81.62$1.63M

Tax

2024-05-03

Guyer Charles Greg

EVP, Chief Technical Officer

4,440 @ $82.44$366K

Sell10b5-1

2024-05-02

Ajer Jeffrey Robert

EVP, Chief Commercial Officer

5,000 @ $82.91$415K

Exercise10b5-1

2024-05-02

Davis George Eric

EVP, Chief Legal Officer

1,850 @ $63.10$117K

Sell10b5-1

2024-05-02

Davis George Eric

EVP, Chief Legal Officer

1,850 @ $85.01$157K

Grant

2024-04-30

FUCHS HENRY J

President, Worldwide R&D

300 @ $68.65$21K

Grant

2024-04-30

Guyer Charles Greg

EVP, Chief Technical Officer

245 @ $68.65$17K

Grant10b5-1

2024-04-30

Ajer Jeffrey Robert

EVP, Chief Commercial Officer

300 @ $68.65$21K

Grant10b5-1

2024-04-30

Davis George Eric

EVP, Chief Legal Officer

301 @ $68.65$21K

Grant10b5-1

2024-04-30

Mueller Brian

EVP, Chief Financial Officer

300 @ $68.65$21K

Date	Insider	Action	Shares	Price	Value
2024-09-30	Friberg Gregory REVP, Chief R&D Officer	Grant	49,850	—	—
2024-09-30	Friberg Gregory REVP, Chief R&D Officer	Grant	7,870	—	—
2024-09-30	Friberg Gregory REVP, Chief R&D Officer	Grant	21,190	—	—
2024-09-13	FUCHS HENRY JPresident, Worldwide R&D	Tax	12,098	$84.90	$1.03M
2024-08-13	Burkhart ErinGVP, Chief Accounting Officer	Sell10b5-1	714	$90.00	$64K
2024-06-28	Mueller BrianEVP, Chief Financial Officer	Tax	588	$82.33	$48K
2024-06-03	HERON ELAINE JDirector	Tax	4,168	$76.41	$318K
2024-06-03	HERON ELAINE JDirector	Exercise	5,047	$63.10	$318K
2024-06-03	MEIER RICHARD ADirector	Tax	5,451	$76.41	$417K
2024-06-03	MEIER RICHARD ADirector	Exercise	6,600	$63.10	$416K
2024-05-30	Mueller BrianEVP, Chief Financial Officer	Exercise10b5-1	5,000	$63.10	$316K
2024-05-30	Mueller BrianEVP, Chief Financial Officer	Sell10b5-1	5,000	$75.19	$376K
2024-05-28	Davis George EricEVP, Chief Legal Officer	Exercise10b5-1	40,850	$63.10	$2.58M
2024-05-28	Davis George EricEVP, Chief Legal Officer	Sell10b5-1	38,071	$74.45	$2.83M
2024-05-28	Davis George EricEVP, Chief Legal Officer	Sell10b5-1	2,779	$75.29	$209K
2024-05-21	Dere Willard HDirector	Grant	4,720	—	—
2024-05-21	HERON ELAINE JDirector	Grant	4,720	—	—
2024-05-21	MEIER RICHARD ADirector	Grant	7,080	—	—
2024-05-21	Bodem Barbara W.Director	Grant	4,720	—	—
2024-05-21	ANDERSON ELIZABETH MDirector	Grant	4,720	—	—
2024-05-21	PYOTT DAVID E IDirector	Grant	4,720	—	—
2024-05-21	Countouriotis AthenaDirector	Grant	4,720	—	—
2024-05-21	Enyedy Mark JDirector	Grant	4,720	—	—
2024-05-21	HOMBACH ROBERT J.Director	Grant	4,720	—	—
2024-05-21	Ho MaykinDirector	Grant	4,720	—	—
2024-05-20	Hubbard CristinEVP, Chief Commercial Officer	Grant	4,700	—	—
2024-05-20	Hubbard CristinEVP, Chief Commercial Officer	Grant	14,690	—	—
2024-05-20	Hubbard CristinEVP, Chief Commercial Officer	Grant	33,520	—	—
2024-05-20	BIENAIME JEAN JACQUESDirector	Tax	1,202	$77.05	$93K
2024-05-17	Burkhart ErinGVP, Chief Accounting Officer	Tax	993	$76.97	$76K
2024-05-10	BIENAIME JEAN JACQUESDirector	Exercise10b5-1	20,000	$63.10	$1.26M
2024-05-10	BIENAIME JEAN JACQUESDirector	Sell10b5-1	20,000	$81.14	$1.62M
2024-05-09	BIENAIME JEAN JACQUESDirector	Exercise10b5-1	20,000	$63.10	$1.26M
2024-05-09	BIENAIME JEAN JACQUESDirector	Sell10b5-1	20,000	$81.62	$1.63M
2024-05-03	Guyer Charles GregEVP, Chief Technical Officer	Tax	4,440	$82.44	$366K
2024-05-02	Ajer Jeffrey RobertEVP, Chief Commercial Officer	Sell10b5-1	5,000	$82.91	$415K
2024-05-02	Davis George EricEVP, Chief Legal Officer	Exercise10b5-1	1,850	$63.10	$117K
2024-05-02	Davis George EricEVP, Chief Legal Officer	Sell10b5-1	1,850	$85.01	$157K
2024-04-30	FUCHS HENRY JPresident, Worldwide R&D	Grant	300	$68.65	$21K
2024-04-30	Guyer Charles GregEVP, Chief Technical Officer	Grant	245	$68.65	$17K
2024-04-30	Ajer Jeffrey RobertEVP, Chief Commercial Officer	Grant10b5-1	300	$68.65	$21K
2024-04-30	Davis George EricEVP, Chief Legal Officer	Grant10b5-1	301	$68.65	$21K
2024-04-30	Mueller BrianEVP, Chief Financial Officer	Grant10b5-1	300	$68.65	$21K

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