FDA approvaloutcome: successconf 1.00

jakafi — FDA approval

$INCY · INCYTE CORP

Event date

September 22, 2021

1718 days ago

Sponsor runway

cash-flow +

$3.46B liquid

Evidence

“openFDA SUPPL (EFFICACY) approval of JAKAFI — application NDA202192”

Source ↗

Comparable historical fda approvals· last 5 years · same event type

100% hit rate (10/10)

Ticker	Drug	Date	Outcome
$INCY	zynyz	2026-05-18	success
$INCY	jakafi xr	2026-05-01	success
$AXSM	auvelity	2026-04-30	success
$INCY	zynyz	2026-03-30	success
$BIIB	spinraza	2026-03-27	success
$CORT	lifyorli	2026-03-25	success
$RYTM	imcivree	2026-03-19	success
$ASND	yuviwel	2026-02-27	success
$BMRN	palynziq	2026-02-27	success
$ETON	desmoda	2026-02-25	success

Recent insider activity· ±90 days

16 insiders · 10 buys · 6 sells

Buy

2021-12-17

BAKER BROS. ADVISORS LP

Director

881,875 @ $72.77$64.18M

Buy

2021-12-17

BAKER BROS. ADVISORS LP

Director

193,997 @ $72.91$14.14M

Buy

2021-12-16

BAKER BROS. ADVISORS LP

Director

29,703 @ $72.00$2.14M

Buy

2021-12-16

BAKER BROS. ADVISORS LP

Director

139,612 @ $71.96$10.05M

Buy

2021-12-15

BAKER BROS. ADVISORS LP

Director

288,368 @ $71.91$20.74M

Buy

2021-12-15

BAKER BROS. ADVISORS LP

Director

861 @ $67.90$58K

Buy

2021-12-15

BAKER BROS. ADVISORS LP

Director

9,352 @ $68.52$641K

Buy

2021-12-15

BAKER BROS. ADVISORS LP

Director

36,476 @ $69.63$2.54M

Buy

2021-12-15

BAKER BROS. ADVISORS LP

Director

9,893 @ $70.24$695K

Buy

2021-12-15

BAKER BROS. ADVISORS LP

Director

5,382 @ $71.03$382K

Tax

2021-12-10

Dhanak Dashyant

EVP & Chief Scientific Officer

533 @ $65.40$35K

Grant

2021-11-19

Stamoulis Christiana

EVP & Chief Financial Officer

379 @ ——

Grant

2021-11-19

Hoppenot Herve

Director

13,279 @ ——

Grant

2021-11-19

Flannelly Barry P

EVP & General Manager US

379 @ ——

Grant

2021-11-19

Hoppenot Herve

Director

2,227 @ ——

Grant

2021-11-19

Pasquale Maria E

EVP & General Counsel

379 @ ——

Grant

2021-11-19

Pasquale Maria E

EVP & General Counsel

2,355 @ ——

Grant

2021-11-19

Iyengar Vijay K

EVP, GMAPPS

379 @ ——

Grant

2021-11-19

Iyengar Vijay K

EVP, GMAPPS

2,355 @ ——

Grant

2021-11-19

Stamoulis Christiana

EVP & Chief Financial Officer

2,355 @ ——

Grant

2021-11-19

SWAIN PAULA J

EVP, Human Resources

379 @ ——

Grant

2021-11-19

Dhanak Dashyant

EVP & Chief Scientific Officer

2,355 @ ——

Grant

2021-11-19

Dhanak Dashyant

EVP & Chief Scientific Officer

379 @ ——

Grant

2021-11-19

Stein Steven H

CMO & Head of Late-Stage Dev.

379 @ ——

Grant

2021-11-19

Stein Steven H

CMO & Head of Late-Stage Dev.

2,355 @ ——

Grant

2021-11-19

SWAIN PAULA J

EVP, Human Resources

2,355 @ ——

Grant

2021-11-19

Flannelly Barry P

EVP & General Manager US

2,355 @ ——

Sell

2021-10-01

Dhanak Dashyant

EVP & Chief Scientific Officer

389 @ $68.67$27K

Grant

2021-09-30

Clancy Paul J

Director

321 @ $68.78$22K

Grant

2021-09-30

DIXON WENDY L

Director

244 @ $68.78$17K

Grant

2021-09-30

HARRIGAN EDMUND

Director

237 @ $68.78$16K

Grant

2021-09-30

FOUSE JACQUALYN A

Director

271 @ $68.78$19K

Grant

2021-09-30

BAKER BROS. ADVISORS LP

Director

393 @ ——

Grant

2021-09-27

BRAWLEY OTIS W

Director

1,255 @ ——

Grant

2021-09-27

BRAWLEY OTIS W

Director

5,910 @ ——

Exercise

2021-09-24

Pasquale Maria E

EVP & General Counsel

382 @ $65.36$25K

Exercise

2021-09-20

SWAIN PAULA J

EVP, Human Resources

1,356 @ $73.21$99K

Sell

2021-09-01

Dhanak Dashyant

EVP & Chief Scientific Officer

388 @ $76.71$30K

Sell

2021-08-02

Dhanak Dashyant

EVP & Chief Scientific Officer

389 @ $77.49$30K

Sell

2021-07-29

Iyengar Vijay K

EVP, GMAPPS

4,911 @ $78.29$384K

Tax

2021-07-06

Iyengar Vijay K

EVP, GMAPPS

401 @ $83.34$33K

Tax

2021-07-06

SWAIN PAULA J

EVP, Human Resources

273 @ $83.34$23K

Tax

2021-07-06

Hoppenot Herve

Director

1,562 @ $83.34$130K

Tax

2021-07-06

Stein Steven H

CMO & Head of Late-Stage Dev.

402 @ $83.34$34K

Tax

2021-07-06

Flannelly Barry P

EVP & General Manager US

273 @ $83.34$23K

Tax

2021-07-06

Trower Paul

Principal Accounting Officer

104 @ $83.34$9K

Tax

2021-07-06

Wenqing Yao

EVP, Head of Discovery Chem

405 @ $83.34$34K

Grant

2021-07-02

Flannelly Barry P

EVP & General Manager US

7,853 @ ——

Grant

2021-07-02

Flannelly Barry P

EVP & General Manager US

15,054 @ ——

Tax

2021-07-02

SWAIN PAULA J

EVP, Human Resources

1,990 @ $83.58$166K

+ 36 more

Date	Insider	Action	Shares	Price	Value
2021-12-17	BAKER BROS. ADVISORS LPDirector	Buy	881,875	$72.77	$64.18M
2021-12-17	BAKER BROS. ADVISORS LPDirector	Buy	193,997	$72.91	$14.14M
2021-12-16	BAKER BROS. ADVISORS LPDirector	Buy	29,703	$72.00	$2.14M
2021-12-16	BAKER BROS. ADVISORS LPDirector	Buy	139,612	$71.96	$10.05M
2021-12-15	BAKER BROS. ADVISORS LPDirector	Buy	288,368	$71.91	$20.74M
2021-12-15	BAKER BROS. ADVISORS LPDirector	Buy	861	$67.90	$58K
2021-12-15	BAKER BROS. ADVISORS LPDirector	Buy	9,352	$68.52	$641K
2021-12-15	BAKER BROS. ADVISORS LPDirector	Buy	36,476	$69.63	$2.54M
2021-12-15	BAKER BROS. ADVISORS LPDirector	Buy	9,893	$70.24	$695K
2021-12-15	BAKER BROS. ADVISORS LPDirector	Buy	5,382	$71.03	$382K
2021-12-10	Dhanak DashyantEVP & Chief Scientific Officer	Tax	533	$65.40	$35K
2021-11-19	Stamoulis ChristianaEVP & Chief Financial Officer	Grant	379	—	—
2021-11-19	Hoppenot HerveDirector	Grant	13,279	—	—
2021-11-19	Flannelly Barry PEVP & General Manager US	Grant	379	—	—
2021-11-19	Hoppenot HerveDirector	Grant	2,227	—	—
2021-11-19	Pasquale Maria EEVP & General Counsel	Grant	379	—	—
2021-11-19	Pasquale Maria EEVP & General Counsel	Grant	2,355	—	—
2021-11-19	Iyengar Vijay KEVP, GMAPPS	Grant	379	—	—
2021-11-19	Iyengar Vijay KEVP, GMAPPS	Grant	2,355	—	—
2021-11-19	Stamoulis ChristianaEVP & Chief Financial Officer	Grant	2,355	—	—
2021-11-19	SWAIN PAULA JEVP, Human Resources	Grant	379	—	—
2021-11-19	Dhanak DashyantEVP & Chief Scientific Officer	Grant	2,355	—	—
2021-11-19	Dhanak DashyantEVP & Chief Scientific Officer	Grant	379	—	—
2021-11-19	Stein Steven HCMO & Head of Late-Stage Dev.	Grant	379	—	—
2021-11-19	Stein Steven HCMO & Head of Late-Stage Dev.	Grant	2,355	—	—
2021-11-19	SWAIN PAULA JEVP, Human Resources	Grant	2,355	—	—
2021-11-19	Flannelly Barry PEVP & General Manager US	Grant	2,355	—	—
2021-10-01	Dhanak DashyantEVP & Chief Scientific Officer	Sell	389	$68.67	$27K
2021-09-30	Clancy Paul JDirector	Grant	321	$68.78	$22K
2021-09-30	DIXON WENDY LDirector	Grant	244	$68.78	$17K
2021-09-30	HARRIGAN EDMUNDDirector	Grant	237	$68.78	$16K
2021-09-30	FOUSE JACQUALYN ADirector	Grant	271	$68.78	$19K
2021-09-30	BAKER BROS. ADVISORS LPDirector	Grant	393	—	—
2021-09-27	BRAWLEY OTIS WDirector	Grant	1,255	—	—
2021-09-27	BRAWLEY OTIS WDirector	Grant	5,910	—	—
2021-09-24	Pasquale Maria EEVP & General Counsel	Exercise	382	$65.36	$25K
2021-09-20	SWAIN PAULA JEVP, Human Resources	Exercise	1,356	$73.21	$99K
2021-09-01	Dhanak DashyantEVP & Chief Scientific Officer	Sell	388	$76.71	$30K
2021-08-02	Dhanak DashyantEVP & Chief Scientific Officer	Sell	389	$77.49	$30K
2021-07-29	Iyengar Vijay KEVP, GMAPPS	Sell	4,911	$78.29	$384K
2021-07-06	Iyengar Vijay KEVP, GMAPPS	Tax	401	$83.34	$33K
2021-07-06	SWAIN PAULA JEVP, Human Resources	Tax	273	$83.34	$23K
2021-07-06	Hoppenot HerveDirector	Tax	1,562	$83.34	$130K
2021-07-06	Stein Steven HCMO & Head of Late-Stage Dev.	Tax	402	$83.34	$34K
2021-07-06	Flannelly Barry PEVP & General Manager US	Tax	273	$83.34	$23K
2021-07-06	Trower PaulPrincipal Accounting Officer	Tax	104	$83.34	$9K
2021-07-06	Wenqing YaoEVP, Head of Discovery Chem	Tax	405	$83.34	$34K
2021-07-02	Flannelly Barry PEVP & General Manager US	Grant	7,853	—	—
2021-07-02	Flannelly Barry PEVP & General Manager US	Grant	15,054	—	—
2021-07-02	SWAIN PAULA JEVP, Human Resources	Tax	1,990	$83.58	$166K

+ 36 more transactions

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